Great write up! Thanks! Regarding step 1 how can any human have an entire homozy... | Hacker News

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mrfusion on July 16, 2020 | parent | context | favorite | on: Researchers generate complete human X chromosome s...

Great write up! Thanks!

Regarding step 1 how can any human have an entire homozygous X chromosome?

Also/rather why not just use a male with one X chromosome?

bmsran on July 16, 2020 [–]

there are long regions on the Y chromosome that are very similar to the X chromosome, which would make the analysis difficult:

https://en.wikipedia.org/wiki/Pseudoautosomal_region

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